منابع مشابه
Wound healing potential of pterospermum acerifolium wild. With induction of tumor necrosis factor - α
Pterospermum acerifolium, a well-known plant in Indian medicine possesses various therapeutic properties including healing properties and cytokine induction. Wound healing activity of ethanolic extract of P. acerifolium flower along with its effect on tumor necrosis factor-α (TNF-α) was assessed using excision model of wound repair in Wistar albino rats. After application of the P. acerifolium ...
متن کاملAccelerated wound healing in tumor necrosis factor receptor p55-deficient mice with reduced leukocyte infiltration.
To clarify biological roles of tumor necrosis factor receptor p55 (TNF-Rp55) -mediated signals in wound healing, skin excisions were prepared in BALB/c (WT) and TNF-Rp55-deficient (KO) mice. In WT mice, the wound area was reduced to 50% of the original area 6 days after injury, with angiogenesis and collagen accumulation. Histopathologically, reepithelialization rate was approximately 80% 6 day...
متن کاملTumor necrosis factor and anti-tumor necrosis factor therapies.
Tumor necrosis factor (TNF) plays a crucial role in the pathogenesis of immune-mediated inflammatory diseases (IMID). As a result, the inhibition of TNF is an important therapeutic avenue in the treatment of these pathophysiologically diverse disease states. This section discusses TNF, its receptors, and its role in immunoregulation and inflammation, as well as the currently available anti-TNF-...
متن کاملEvaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...
متن کاملEffect of Collagen Membrane on Tumor Necrosis Factor-Alpha (TNF-α) Level in Wound Healing Process in Rats
This study aimed to measure the TNF-α level in rat blood serum during wound healing process using collagen membrane. Methods: 24 male Wistar rats were divided into two groups: treatment and control. A bone defect was created on the rat’s jaw using a 2 mm diamond bur. The defect was then covered with collagen membrane in the treatment group and without collagen membrane cover in control group. R...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1990
ISSN: 0003-4932
DOI: 10.1097/00000658-199002000-00002